Inactivation kinetics and lethal dose analysis of antimicrobial blue light and photodynamic therapy

CP Sabino, M Wainwright, C Dos Anjos… - Photodiagnosis and …, 2019 - Elsevier
Abstract Background Antimicrobial Photodynamic therapy (A-PDT) has been used to treat
infections. Currently, microbial inactivation data is reported presenting survival fraction
averages and standard errors as discrete points instead of a continuous curve of inactivation
kinetics. Standardization of this approach would allow clinical protocols to be introduced
globally, instead of the piecemeal situation which currently applies. Methods To this end, we
used a power-law function to fit inactivation kinetics and directly report values of lethal doses …