Conjunctival goblet cells: Ocular surface functions, disorders that affect them, and the potential for their regeneration

SK Swamynathan, A Wells - The ocular surface, 2020 - Elsevier
Conjunctival goblet cells (CGCs) are specialized cells that produce and secrete soluble
mucins to the tear film that bathes the ocular surface. CGC numbers and functions are
affected in various ocular surface diseases including dry eye disease with diverse etiologies.
In this review we will (i) summarize the important functions of CGCs in ocular surface
health,(ii) describe the ocular surface diseases that affect CGC numbers and function,(iii)
provide an update on recent research outcomes that elucidate CGC differentiation, gene …