[HTML][HTML] Noise exposure immediately activates cochlear mitogen-activated protein kinase signaling
KN Alagramam, R Stepanyan, S Jamesdaniel… - Noise and …, 2014 - journals.lww.com
Noise-induced hearing loss (NIHL) is a major public health issue worldwide. Uncovering the
early molecular events associated with NIHL would reveal mechanisms leading to the
hearing loss. Our aim is to investigate the immediate molecular responses after different
levels of noise exposure and identify the common and distinct pathways that mediate NIHL.
Previous work showed mice exposed to 116 decibels sound pressure level (dB SPL)
broadband noise for 1 h had greater threshold shifts than the mice exposed to 110 dB SPL …
early molecular events associated with NIHL would reveal mechanisms leading to the
hearing loss. Our aim is to investigate the immediate molecular responses after different
levels of noise exposure and identify the common and distinct pathways that mediate NIHL.
Previous work showed mice exposed to 116 decibels sound pressure level (dB SPL)
broadband noise for 1 h had greater threshold shifts than the mice exposed to 110 dB SPL …
